Researchers suggest thatobesityis a chronic disease with a number of biological causes that make it impossible to be cured withdiet and exercisealone in a recently published comment inThe Lancet Diabetes & Endocrinology.
Eighty percent to 95% of people with obesity who lose weight eventually regain it. Several biological systems are triggered when caloric intake is reduced, which drives people to eat more high-calorie foods and, in turn, gain or regain weight. According to the researchers lifestyle changes are not enough to override the fat-loss defense for most individuals with sustained obesity.
Although lifestyle modifications may result in lasing weight loss in individuals who are overweight, in those with sustained obesity, bodyweight seems to become biologically stamped in and defended,Christopher N. Ochner, PhD,assistant professor of pediatrics and psychiatry at Icahn School of Medicine at Mount Sinai and a research associate at the New York Obesity Nutrition Research Center at Columbia University Medical Center, said in a press release. Therefore, the current advice to eat less and exercise more may be no more effective for most individuals with obesity than a recommendation to avoid sharp objects for someone bleeding profusely. (more)
Ochner CN, et al. Lancet Diabetes Endocrinol. 2015;doi:10.1016/S2213-8587(15)70010.